Yamla Pagla Deewana opened with a good response in the theatres and earned well. On the weekdays, the film also performed well and took its first week total to a very good value. On the second week too, it collected an excellent amount and also got the benefit of the holiday due to Republic day.
The film lasted at the box office for several weeks and took its lifetime total over Rs. 50 crores. Due to its excellent earning in the overseas, it fared well and collected over Rs. 30 crores. It helped the comedy film to take its worldwide collection over Rs. 85 crores. Because of its successful journey in the theatres, the makers came with its sequels in the coming years.